X-RAY MEDICAL DIAGNOSTICS AS A RISK FACTOR FOR MYELOID LEUKEMIA IN BULGARIAN POPULATION

Nina Chobanova and Antonina Bayrakova1

National Center of Radiobiology and Radiation Protection, Sofia, Bulgaria
 
Corresponding author: Nina Chobanova, M. D.
National Center of Radiobiology and Radiation Protection,
132, Kl. Ohridsky Blvd.
1756 Sofia, Bulgaria
Fax: (+359) 2 621 059
Tel.: (+359) 2 626 037


CEJOEM 1999 5(2):130-135


ABSTRACT: The medical X-ray diagnostics is the dominant „man-made” source of radiation exposure to the Bulgarian population. The aim of this study is to evaluate the relationship between exposure from medical X-ray diagnostic procedures and the occurrence at the myeloid leukemia. The assessment is based on analytical epidemiological study of a case-control type. Investigation was made on 132 cases with acute and chronic myeloid leukemia and 264 controls matched by sex and age. The risk factor assessment is based on the red bone marrow dose (mSv) cumulated from the different X-ray diagnostic procedures as well as on the distribution of investigated persons depending on the type and number of procedures. The results from the present study prove the impact of X-ray diagnostics as a risk factor to myeloid leukemia.

KEY WORDS: Medical X-ray diagnostics, myeloid leukemia, radiation risk, case-control study


Received: 18 November 1998
Accepted: 28 July 1999

Posted: December 1999

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